Hiesele leads a DP World Tour event for the first time in his career after he endured a difficult season in 2021, making just four cuts before cutting his season short in September.
“I had my thyroid removed in early October and I feel like a new man more or less,” Heisele said.
“I turned things around for the better for me so I’m happy I got it done. I couldn’t imagine sat on the plane that it would be like this, I was a bit nervous and didn’t know what to expect. I had a few decent days of practice leading up to today obviously and made the most of it.”
Co-leader Jamieson got off to a fast start for a second-consecutive week after he led the first three rounds of the Dubai Desert Classic last time out.
Information from the Associated Press contributed to this report.